Research Activity
Chief Investigator, SCIL Study. Active research in vestibular schwannomas, NF2 and meningiomas
Publications
1. Disease course of Neurofibromatosis Type 2; a 30-year follow-up study of 353 patients seen at a single institution.
Forde C, King AT, Rutherford SA, Hammerbeck-Ward C, Lloyd SK, Freeman SR, Pathmanaban ON, Stapleton E, Thomas OM, Laitt RD, Stivaros S, Kilday JP, Vassallo G, McBain C, Kerrigan S, Smith MJ, McCabe MG, Harkness EF, Evans DG.
Neuro Oncol. 2020 Dec 18:noaa284. doi: 10.1093/neuonc/noaa284. Online ahead of print.
2. Trial of Dexamethasone for Chronic Subdural Hematoma.
Hutchinson PJ, Edlmann E, Bulters D, Zolnourian A, Holton P, Suttner N, Agyemang K, Thomson S, Anderson IA, Al-Tamimi YZ, Henderson D, Whitfield PC, Gherle M, Brennan PM, Allison A, Thelin EP, Tarantino S, Pantaleo B, Caldwell K, Davis-Wilkie C, Mee H, Warburton EA, Barton G, Chari A, Marcus HJ, King AT, Belli A, Myint PK, Wilkinson I, Santarius T, Turner C, Bond S, Kolias AG; British Neurosurgical Trainee Research Collaborative; Dex-CSDH Trial Collaborators.
N Engl J Med. 2020 Dec 31;383(27):2616-2627. doi: 10.1056/NEJMoa2020473. Epub 2020 Dec 16.
3. The spatial phenotype of genotypically distinct meningiomas demonstrate potential implications of the embryology of the meninges.
Fountain DM, Smith MJ, O'Leary C, Pathmanaban ON, Roncaroli F, Bobola N, King AT, Evans DG.
Oncogene. 2020 Dec 1. doi: 10.1038/s41388-020-01568-6. Online ahead of print.
4. The importance of genetic counseling and screening for people with pathogenic SMARCE1 variants: A family study.
Shoakazemi A, Hewitt A, Smith MJ, du Plessis D, Thomas O, Stivaros SM, Deniz K, Hammerbeck-Ward C, Rutherford SA, King AT, Evans DG.
Am J Med Genet A. 2020 Nov 13. doi: 10.1002/ajmg.a.61970. Online ahead of print.
5. The inflammatory microenvironment in vestibular schwannoma.
Hannan CJ, Lewis D, O'Leary C, Donofrio CA, Evans DG, Roncaroli F, Brough D, King AT, Coope D, Pathmanaban ON.
Neurooncol Adv. 2020 Feb 27;2(1):vdaa023. doi: 10.1093/noajnl/vdaa023.
6. The microenvironment in sporadic and neurofibromatosis type II-related vestibular schwannoma: the same tumor or different? A comparative imaging and neuropathology study.
Lewis D, Donofrio CA, O'Leary C, Li KL, Zhu X, Williams R, Djoukhadar I, Agushi E, Hannan CJ, Stapleton E, Lloyd SK, Freeman SR, Wadeson A, Rutherford SA, Hammerbeck-Ward C, Evans DG, Jackson A, Pathmanaban ON, Roncaroli F, King AT, Coope DJ.
J Neurosurg. 2020 May 29:1-11. doi: 10.3171/2020.3.JNS193230. Online ahead of print.
7. Hampering brain tumor proliferation and migration using peptide nanofiber:siPLK1/MMP2 complexes.
Mazza M, Ahmad H, Hadjidemetriou M, Agliardi G, Pathmanaban ON, King AT, Bigger BW, Vranic S, Kostarelos K.
Nanomedicine (Lond). 2019 Dec;14(24):3127-3142. doi: 10.2217/nnm-2019-0298.
8. Academic neurosurgery in the UK: present and future directions.
Waqar M, Davies BM, Zakaria R, Barone DG, Kolias AG, Yu KK, Ellenbogen JR, Brennan PM, Kotter MR, Gray WP, King AT, Turner C, Kitchen N, May P, Jenkinson MD, Hutchinson PJ.
Postgrad Med J. 2019 Oct;95(1128):524-530. doi: 10.1136/postgradmedj-2019-136805. Epub 2019 Aug 20.
9. Incidence of mosaicism in 1055 de novo NF2 cases: much higher than previous estimates with high utility of next-generation sequencing.
Evans DG, Hartley CL, Smith PT, King AT, Bowers NL, Tobi S, Wallace AJ, Perry M, Anup R, Lloyd SKW, Rutherford SA, Hammerbeck-Ward C, Pathmanaban ON, Stapleton E, Freeman SR, Kellett M, Halliday D, Parry A, Gair JJ, Axon P, Laitt R, Thomas O, Afridi SK, Obholzer R; English Specialist NF research group, Duff C, Stivaros SM, Vassallo G, Harkness EF, Smith MJ.
Genet Med. 2020 Jan;22(1):53-59. doi: 10.1038/s41436-019-0598-7. Epub 2019 Jul 5.
10. [18F]fluorothymidine and [18F]fluorodeoxyglucose PET Imaging Demonstrates Uptake and Differentiates Growth in Neurofibromatosis 2 Related Vestibular Schwannoma.
Anton-Rodriguez JM, Lewis D, Djoukhadar I, Russell D, Julyan P, Coope D, King AT, Lloyd SKL, Evans DG, Jackson A, Matthews JC.
Otol Neurotol. 2019 Apr 19. doi: 10.1097/MAO.0000000000002272. [Epub ahead of print
11. Influence of Antiplatelet and Anticoagulant Drug Use on Outcomes after Chronic Subdural Hematoma Drainage.
Poon MTC, Rea C, Kolias AG, Brennan PM; British Neurosurgical Trainee Research Collaborative (BNTRC).
J Neurotrauma. 2019 Jan 30. doi: 10.1089/neu.2018.6080. [Epub ahead of print
12. Identifying the deficiencies of current diagnostic criteria for neurofibromatosis 2 using databases of 2777 individuals with molecular testing.
Evans DG, King AT, Bowers NL, Tobi S, Wallace AJ, Perry M, Anup R, Lloyd SKL, Rutherford SA, Hammerbeck-Ward C, Pathmanaban ON, Stapleton E, Freeman SR, Kellett M, Halliday D, Parry A, Gair JJ, Axon P, Laitt R, Thomas O, Afridi S, Ferner RE, Harkness EF, Smith MJ; English Specialist NF2 Research Group.
Genet Med. 2018 Dec 7. doi: 10.1038/s41436-018-0384-y. [Epub ahead of print]]
13. Inflammation and Vascular Permeability Correlate With Growth in Sporadic Vestibular Schwannoma.
Lewis D, Roncaroli F, Agushi E, Mosses D, Williams R, Li KL, Zhu X, Hinz R, Atkinson R, Wadeson A, Hulme S, Mayers H, Stapleton E, Lloyd SKL, Freeman SR, Rutherford SA, Hammerbeck-Ward C, Evans DG, Pathmanaban O, Jackson A, King AT, Coope D.
Neuro Oncol. 2018 Nov 2. doi: 10.1093/neuonc/noy177. [Epub ahead of print]
14. Familial unilateral vestibular schwannoma is rarely caused by inherited variants in the NF2 gene.
Evans DG, Wallace AJ, Hartley C, Freeman SR, Lloyd SK, Thomas O, Axon P, Hammerbeck-Ward CL, Pathmanaban O, Rutherford SA, Kellett M, Laitt R, King AT, Bischetsrieder J, Blakeley J, Smith MJ.
Laryngoscope. 2019 Apr;129(4):967-973. doi: 10.1002/lary.27554. Epub 2018 Oct 16.
15. Does Drain Position and Duration Influence Outcomes in Patients Undergoing Burr-Hole Evacuation of Chronic Subdural Hematoma? Lessons from a UK Multicenter Prospective Cohort Study.
Glancz LJ, Poon MTC, Coulter IC, Hutchinson PJ, Kolias AG, Brennan PM; British Neurosurgical Trainee Research Collaborative (BNTRC) .
Neurosurgery. 2018 Aug 29. doi: 10.1093/neuros/nyy366. [Epub ahead of print]
16. Schwannomatosis: a genetic and epidemiological study.
Evans DG, Bowers NL, Tobi S, Hartley C, Wallace AJ, King AT, Lloyd SKW, Rutherford SA, Hammerbeck-Ward C, Pathmanaban ON, Freeman SR, Ealing J, Kellett M, Laitt R, Thomas O, Halliday D, Ferner R, Taylor A, Duff C, Harkness EF, Smith MJ.
J Neurol Neurosurg Psychiatry. 2018 Nov;89(11):1215-1219. doi: 10.1136/jnnp-2018-318538. Epub 2018 Jun 16.
17. Outcomes following surgery in subgroups of comatose and very elderly patients with chronic subdural hematoma.
Christopher E, Poon MTC, Glancz LJ, Hutchinson PJ, Kolias AG, Brennan PM; British Neurosurgical Trainee Research Collaborative (BNTRC).
Neurosurg Rev. 2019 Jun;42(2):427-431. doi: 10.1007/s10143-018-0979-4. Epub 2018 Apr 21.
18. New drug candidates for treatment of atypical meningiomas: An integrated approach using gene expression signatures for drug repurposing.
Zador Z, King AT, Geifman N.
PLoS One. 2018 Mar 20;13(3):e0194701. doi: 10.1371/journal.pone.0194701. eCollection 2018.
19. Spinal ependymomas in NF2: a surgical disease?
Kalamarides M, Essayed W, Lejeune JP, Aboukais R, Sterkers O, Bernardeschi D, Peyre M, Lloyd SK, Freeman S, Hammerbeck-Ward C, Kellett M, Rutherford SA, Evans DG, Pathmanaban O, King AT.
J Neurooncol. 2018 Feb;136(3):605-611. doi: 10.1007/s11060-017-2690-7. Epub 2017 Nov 29
20. Malignant Peripheral Nerve Sheath Tumors are not a Feature of Neurofibromatosis Type 2 in the Unirradiated Patient
King, AT; Rutherford, SA; Hammerbeck-Ward, C; Lloyd, SK; Freeman, SR; Pathmanaban, ON; Kellett, M; Obholzer, R; Afridi, S; Axon, P; Halliday, D; Parry, A; Thomas, OM; Laitt, RD; McCabe, MG; Stivaros, S; Erridge, S; Evans, DG; English Specialist NF2 research group
Neurosurgery 2017 Jul 20. doi: 20.2093/neuros/nyx368
21. High-Grade Glioma is not a Feature of Neurofibromatosis Type 2 in the Unirradiated Patient
King, AT; Rutherford, SA; Hammerbeck-Ward, C; Lloyd, SK; Freeman, SM; Pathmanaban, ON; Rodriguez-Valero, M; Thomas, OM; Laitt, RD; Stivaros, S; Kellett, M; Evans, DG
Neurosurgery 2017 Jul 21. Doi: 10.1093/neuros/nyx374 [Epub ahead of print]
22. Long-term Quality of Life Following Vestibular Schwannoma Excision via the Translabyrinthine Approach
Broomfield, SJ; Mandavia, AK; Nicholson, JS; Mahmoud, O; King, AT; Rutherford, SA; Ramsden, RT
Otol. Neurotol., 2017 vol. 38(8) pp. 1165-1173
23. Association of Genetic Predisposition With Solitary Schwannoma or Meningioma in Children and Young Adults
Pathmanaban, ON; Sadler, KV; Kamaly-Asl, ID; King, AT; Rutherford, SA; Hammerbeck-Ward, C; McCabe, MG; Kilday, JP; Beetz, C; Poplawski, NK; Evans, DG; Smith, MJ
JAMA Neurol, 2017 vol. 74(9) pp. 1123-1129
24. Safety of Superior Petrosal Vein Sacrifice During Microvascular Decompression of the Trigeminal Nerve
Pathmanaban, ON; O'Brien, F; Al-Tamimi, YZ; Hammerbeck-Ward, CL; Rutherford, SA; King, AT
World Neurosurg, 2017 vol. 103 pp. 84-87
25. Hearing optimisation in neurofibromatosis type 2: A systematic review
Lloyd, SKW; King, AT; Rutherford, SA; Hammerbeck-Ward, CL; Freeman, SRM; Mawman, DJ; O'Driscoll, M; Evans, DG
Clin Otolaryngol, 2017
26. Reduction of inflammation after administration of interleukin-1 receptor antagonist following aneurysmal subarachnoid hemorrhage: results of the Subcutaneous Interleukin-1Ra in SAH (SCIL-SAH) study.
Galea J, Ogungbenro K, Hulme S, Patel H, Scarth S, Hoadley M, Illingworth K, McMahon CJ, Tzerakis N, King AT, Vail A, Hopkins SJ, Rothwell N, Tyrrell P.
J Neurosurg. 2017 Feb 24:1-9.
27. Revisiting neurofibromatosis type 2 diagnostic criteria to exclude LZTR1-related schwannomatosis.
Smith MJ, Bowers NL, Bulman M, Gokhale C, Wallace AJ, King AT, Lloyd SK, Rutherford SA, Hammerbeck-Ward CL, Freeman SR, Evans DG.
Neurology. 2017 Jan 3;88(1):87-92.
28. The management and outcome for patients with chronic subdural hematoma: a prospective, multicenter, observational cohort study in the United Kingdom
Brennan PM, Kolias AG, Joannides AJ, Shapey J, Marcus HJ, Gregson BA, Grover PJ, Hutchinson PJ, Coulter IC; on behalf of the British Neurosurgical Trainee Research Collaborative.
J Neurosurg. 2016 Nov 11:1-8. [Epub ahead of print]
29. Outcomes of cochlear implantation in patients with neurofibromatosis type 2
North HJ, Mawman D, O'Driscoll M, Freeman SR, Rutherford SA, King AT, Hammerbeck-Ward C, Evans DG, Lloyd SK.
Cochlear Implants Int. 2016 Jul;17(4):172-177.
30. Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension.
Hutchinson PJ, Kolias AG, Timofeev IS, Corteen EA, Czosnyka M, Timothy J, Anderson I, Bulters DO, Belli A, Eynon CA, Wadley J, Mendelow AD, Mitchell PM, Wilson MH, Critchley G, Sahuquillo J, Unterberg A, Servadei F, Teasdale GM, Pickard JD, Menon DK, Murray GD, Kirkpatrick PJ; RESCUEicp Trial Collaborators.
N Engl J Med. 2016 Sep 22;375(12):1119-30.
31. Auditory Brainstem Implantation in Neurofibromatosis Type 2: Experience From the Manchester Programme.
Ramsden RT, Freeman SR, Lloyd SK, King AT, Shi X, Ward CL, Huson SM, Mawman DJ, O'Driscoll MP, Evans DG, Rutherford SA; Manchester Neurofibromatosis Type 2 Service.
Otol Neurotol. 2016 Oct;37(9):1267-74.
32. Predictors of Outcome in Traumatic Brain Injury: New Insight Using Receiver Operating Curve Indices and Bayesian Network Analysis.
Zador Z, Sperrin M, King AT.
PLoS One. 2016 Jul 7;11(7):e0158762
33. Intraoperative Supratentorial Extradural Hematoma Complicating Excision of a Giant Vestibular Schwannoma.
Lewis DG, Lloyd S, Pathmanaban ON, Hammerbeck-Ward C, Rutherford SA, King AT.
World Neurosurg. 2016 May;89:726.e15-7.
34. Clinical and molecular predictors of mortality in neurofibromatosis 2: a UK national analysis of 1192 patients.
Hexter A, Jones A, Joe H, Heap L, Smith MJ, Wallace AJ, Halliday D, Parry A, Taylor A, Raymond L, Shaw A, Afridi S, Obholzer R, Axon P, King AT; English Specialist NF2 Research Group, Friedman JM, Evans DG.
J Med Genet. 2015 Oct;52(10):699-705.
35. Rapid Increase in Neural Conduction Time in the Adult Human Auditory Brainstem Following Sudden Unilateral Deafness.
Maslin MR, Lloyd SK, Rutherford S, Freeman S, King A, Moore DR, Munro KJ.
J Assoc Res Otolaryngol. 2015 Oct;16(5):631-40
36. Multiple synchronous sites of origin of vestibular schwannomas in neurofibromatosis Type 2.
Stivaros SM, Stemmer-Rachamimov AO, Alston R, Plotkin SR, Nadol JB, Quesnel A, O'Malley J, Whitfield GA, McCabe MG, Freeman SR, Lloyd SK, Wright NB, Kilday JP, Kamaly-Asl ID, Mills SJ, Rutherford SA, King AT, Evans DG.
J Med Genet. 2015 Aug;52(8):557-62.
37. Bilateral vestibular schwannomas in older patients: NF2 or chance?
Evans DG, Freeman S, Gokhale C, Wallace A, Lloyd SK, Axon P, Ward CL, Rutherford S, King A, Huson SM, Ramsden RT; Manchester NF2 service.
J Med Genet. 2015 Jun;52(6):422-4.
38. Reply to Comment on 'Pitfalls in microdialysis methodology: an in vitro analysis of temperature, pressure and catheter use'.
Galea JP, Tyrrell PJ, Patel HP, Vail A, King AT, Hopkins SJ.
Physiol Meas. 2015 Mar;36(3):623-4.
39. Subjective Outcomes of Auditory Brainstem Implantation.
McSorley A, Freeman SR, Ramsden RT, Motion J, King AT, Rutherford SA, Mawman DJ, O’Driscoll MP, Wickham Lloyd SK.
Otol Neurotol. 2014 Dec 3
40. Progress of hearing loss in neurofibromatosis type 2: implications for future management.
Kontorinis G, Nichani J, Freeman SR, Rutherford SA, Mills S, King AT, Mawman D, Huson S, O'Driscoll M, Gareth Evans D, Lloyd SK.
Eur Arch Otorhinolaryngol. 2014 Oct 8.
41. Clinical and Radiological Guidance in Managing Facial Nerve Schwannomas.
Doshi J, Heyes R, Freeman SR, Potter GM, Ward CL, Rutherford SA, King AT, Ramsden RT, Lloyd SK.
Otol Neurotol. 2014 Oct 17.
42. Surgical outcomes in cystic vestibular schwannoma versus solid vestibular schwannoma.
Tang IP, Freeman SR, Rutherford SA, King AT, Ramsden RT, Lloyd SK.
Otol Neurotol. 2014 Aug;35(7):1266-70.
43. Simvastatin in aneurysmal subarachnoid haemorrhage (STASH): a multicentre randomised phase 3 trial.
Kirkpatrick PJ1, Turner CL2, Smith C1, Hutchinson PJ1, Murray GD3; STASH Collaborators (I was a collaborator).
Lancet Neurol. 2014 Jul;13(7):666-75 2014 May 15.
44. Geniculate neuralgia: a systematic review.
Tang IP, Freeman SR, Kontorinis G, Tang MY, Rutherford SA, King AT, Lloyd SK.
J Laryngol Otol. 2014 May;128(5):394-9.
45. Management of cerebellopontine angle lipomas: need for long-term radiologic surveillance?
Kontorinis G, Freeman SR, Potter G, Rutherford SA, Siripurapu R, King AT, Lloyd SK.
Otol Neurotol. 2014 Jun;35(5):e163-8.
46. Pitfalls in microdialysis methodology: an in vitro analysis of temperature, pressure and catheter use.
Galea JP, Tyrrell PJ, Patel HP, Vail A, King AT, Hopkins SJ.
Physiol Meas. 2014 Mar;35(3):N21-8
47. The effect of intravenous interleukin-1 receptor antagonist on inflammatory mediators in cerebrospinal fluid after subarachnoid haemorrhage: a phase II randomised controlled trial.
Singh N, Hopkins SJ, Hulme S, Galea JP, Hoadley M, Vail A, Hutchinson PJ, Grainger S, Rothwell NJ, King AT, Tyrrell PJ.
J Neuroinflammation. 2014 Jan 3;11:1.
48. Ipsilateral cochlear implantation after cochlear nerve preserving vestibular schwannoma surgery in patients with neurofibromatosis type 2.
Lloyd SK, Glynn FJ, Rutherford SA, King AT, Mawman DJ, O'Driscoll MP, Evans DG, Ramsden RT, Freeman SR.
Otol Neurotol. 2014 Jan;35(1):43-51.
49. Which factors influence decisions to transfer and treat patients with acute intracerebral haemorrhage and which are associated with prognosis? A retrospective cohort study.
Abid KA, Vail A, Patel HC, King AT, Tyrrell PJ, Parry-Jones AR.
BMJ Open. 2013 Dec 17;3(12):e003684.
50. English consensus protocol evaluating candidacy for auditory brainstem and cochlear implantation in neurofibromatosis type 2.
Tysome JR, Axon PR, Donnelly NP, Evans DG, Ferner RE, O'Connor AF, Freeman SR, Gleeson M, Halliday D, Harris F, Jiang D, Kerr R, King A, Knight RD, Lloyd SK, Macfarlane R, Mannion R, Mawman D, O'Driscoll M, Parry A, Ramsden J, Ramsden R, Rutherford SA, Saeed SR, Thomas N, Vanat ZH.
Otol Neurotol. 2013 Dec;34(9):1743-7.
51. The management of cochlear nerve deficiency.
Freeman SR, Stivaros SM, Ramsden RT, O'Driscoll MP, Nichani JR, Bruce IA, Green KM, Henderson LA, Rutherford SA, King AT, Lloyd SK.
Cochlear Implants Int. 2013 Nov;14 Suppl 4:S27-31.
52. Pilot study of perioperative accidental durotomy: does the period of postoperative bed rest reduce the incidence of complication?
Low JC, von Niederhäusern B, Rutherford SA, King AT.
Br J Neurosurg. 2013 Dec;27(6):800-2.
53. Accuracy and clinical usefulness of intracerebral hemorrhage grading scores: a direct comparison in a UK population.
Parry-Jones AR, Abid KA, Di Napoli M, Smith CJ, Vail A, Patel HC, King AT, Tyrrell PJ.
Stroke. 2013 Jul;44(7):1840-5.
54. Surgical management of acute subdural haematomas: current practice patterns in the United Kingdom and the Republic of Ireland.
Kolias AG, Scotton WJ, Belli A, King AT, Brennan PM, Bulters DO, Eljamel MS, Wilson MH, Papadopoulos MC, Mendelow AD, Menon DK, Hutchinson PJ; UK Neurosurgical Research Network; RESCUE-ASDH collaborative group.
Br J Neurosurg. 2013 Jun;27(3):330-3.
55. Factors Influencing Decision-making and Outcome in the Surgical Management of Trigeminal Neuralgia.
Ammori MB, King AT, Siripurapu R, Herwadkar AV, Rutherford SA.
J Neurol Surg B Skull Base. 2013 Apr;74(2):75-81.
56. Cerebrospinal fluid and cytokines after subarachnoid haemorrhge: CSF interleukin-6 may be an early marker of infection.
Hopkins SJ, McMahon CJ, Singh N, Galea J, Hoadley M, Scarth S, Patel H, Vail A, Hulme S, Rothwell NJ, King AT, Tyrrell PJ.
J Neuroinflammation. 2012 Nov 23; 9:255
57. Inflammation as a predictor for delayed cerebral ischemia after aneurysmal subarachnoid haemorrhage.
McMahon CJ, Hopkins S, Vail A, King AT, Smith D, Illingworth KJ, Clark S, Rothwell NJ, Tyrrell PJ.
J Neurointerv Surg. 2012 Oct 11
58. Imaging in young adults with intracerebral hemorrhage
Kirkman MA, Tyrrell PJ, King AT, Patel HC.
Clin Neurol Neurosurg 2012 Apr 21
59. External ventricular drain infection: improved technique can reduce infection rates.
Kitchen WJ, Singh N, Hulme S, Galea J, Patel HC, King AT
Br J Neurosurgery 2011 Oct; 25(5):632-5
60. The importance of angiographic and venographic cranial imaging in intracerebral hemorrhage occurring during pregnancy and the puerperium.
Kirkman MA, Tyrrell PJ, King AT, Patel HC.
Eur J Neurol 2011 Sep;18(9):e112-3.
61. Difficulties with recruiting into neurosurgical clinical trials: the Surgical Trial in Intracerebral Haemorrhage II as an example.
Kirkman MA, Greenwood N, Singh N, Tyrrell PJ, King AT, Patel HC.
Br J Neurosurgery 2011 April; 25(2):231-4
62. Cranial meningiomas in 411 neurofibromatosis type 2 (NF2) patients with proven gene mutations: clear positional effect of mutations, but absence of female severity effect on age at onset.
Smith MJ, Higgs JE, Bowers NL, Halliday D, Paterson J, Gillespie J, Huson SM, Freeman SR, Lloyd S, Rutherford SA, King AT, Wallace AJ, Ramsden RT, Evans DG.
J Med Genet. 2011 Apr; 48(4):261-5.
63. Intravenous anakinra can achieve experimentally effective concentrations in the central nervous system within a therapeutic time window: results of a dose-ranging study.
Galea J, Ogungbenro K, Hulme S, Greenhalgh A, Aarons L, Scarth S, Hutchinson P, Grainger S, King A, Hopkins SJ, Rothwell N, Tyrrell P.
J Cereb Blood Flow Metab. 2011 Feb; 31(2):439-47.
64. The effect of spontaneous alterations in brain temperature on outcome: a prospective observational cohort study in patients with severe traumatic brain injury.
Sacho RH, Vail A, Rainey T, King AT, Childs C.
J Neurotrauma. 2010 Dec; 27(12):2157-64
65. Rates of loss of heterozygosity and mitotic recombination in NF2 schwannomas, sporadic vestibular schwannomas and schwannomatosis schwannomas.
Hadfield KD, Smith MJ, Urquhart JE, Wallace AJ, Bowers NL, King AT, Rutherford SA, Trump D, Newman WG, Evans DG.
Oncogene. 2010 Nov 25; 29(47):6216-21.
66. Vestibular schwannoma: role of conservative management.
Suryanarayan R, Ramsden RT, Saeed SR, Aggarwal R, King AT, Rutherford SA, Evans DG, Gillespie JE
J Laryngol Otol.2010 Mar;123(3) 251-7
67. The surgical management and outcomes for spheno-orbital meningiomas: a 7 year review of a multidisciplinary practice.
Cannon PS, Rutherford SA, Richardson PL, King A, Leatherbarrow B
Orbit. 2009: 28(6):371-6
68. Outcome from surgery for vestibular schwannomas in children.
MacNally SP, Rutherford SA, King AT, Freeman S, Thorne J, Mawman D, O’Driscoll MP, Evans DG, Ramsden RT.
Br J Neurosurgery. 2009 Jun; 23(3): 226-31
69. Outcome after severe head injury: focal surgical lesions do not imply a better Glasgow Outcome Score than diffuse injuries at 3 months.
Leach P, Pathmanaban ON, Patel HC, Evans J, Sacho R, Protheroe R, King AT.
J Trauma Manag Outcomes. 2009 Apr 3;3:5
70. Trigeminal schwannomas
MacNally SP, Rutherford SA, Ramsden RT, Evans DG, King AT
Br J Neurosurgery. 2008 Dec; 22(6): 729-38
71. Enterogenous cysts of the cerebellopontine angle: short review illustrated by two new patients.
Perrini P, Rutherford SA, King AT, du Plessis D, Di Lorenzo N.
Acta Neurochir (Wein). 2008 Feb; 150(2);177-84 discusion 184
72. Revision surgery for residual or recurrent vestibular schwannoma.
Freeman SR, Ramsden RT, Saeed SR, Alzoubi FQ, Simo R, Rutherford SR, King AT.
Otol Neurotol. 2007; 28(8):1076-1082
73. The reproducibility of transcranial Doppler middle cerebral artery velocity measurements: implications for clinical practice.
McMahon CJ, McDermott P, Horsfall D, Selvarajah JR, King AT, Vail A.
Br J Neurosurg. 2007 Feb;21(1):21-7
74. Transfer times for patients with extradural and subdural haematomas to neurosurgery in Greater Manchester.
Leach P, Childs C, Evan J, Johnston N, Protheroe R, King A.
Br J Neurosurg 2007 Feb: 21(1): 11-5
75. Body temperature management after severe traumatic brain injury: methods and protocols used in the United Kingdom and Ireland.
Johnson NJ, King AT, Protheroe R, Childs C.
Resuscitation. 2006 Aug;70(2):254-62.
76. Brain temperature and outcome after severe traumatic brain injury.
Childs C, Vail A, Leach P, Rainey T, Protheroe R, King A.
Neurocritical Care 2006(5): 1-5
77. Trends in head injury outcome from 1989 to 2003 and the effect of neurosurgical care: an observational study.
Patel HC, Bourama O, Woodford M, King AT, Yates DW, Lecky FE.
Lancet 2005 Oct 4; 366(9464): 1538-44
78. Vestibular schwannoma management: What is the “best” option?
Rutherford SA King AT
British Journal of Neurosurgery 2005 Aug; 19(4): 309-316
79. Spinal tumors in neurofibromatosis type 2. Is emerging knowledge of genotype predictive of natural history?
Dow G. Biggs N. Evans G. Gillespie J. Ramsden R. King A.
Journal of Neurosurgery Spine. 2(5):574-9, 2005 May.
80. Differences between brain and rectal temperatures during routine critical care of patients with severe traumatic brain injury.
Childs C, Vail A Protheroe R, King AT, Dark PM.
Anaesthesia Aug 2005 60(8) ; 759-765
81. Multiple Meningiomas: differential involvement of the NF2 gene in children and adults.
DGR Evans, C Watson, A King, AJ Wallace, ME Baser.
J Med Genet. 2005 Jan; 42(1) 45-8
82. Incidence of vestibular schwannoma and neurofibromatosis type 2 in the North West of England over a 10 year period: higher incidence than previously thought.
Evans DGR, Moran A, King AT, Saeed S, Gurusinghe N, Ramsden R.
Otol Neurotol Jan 2005: 26(1); 93-7
83. Generic waiting lists for routine spinal surgery.
Leach P, Rutherford S, King AT, Leggate JRS.
Journal of the Royal Society of Medicine. Mar 2004 97 (3): 119-120
84. Spinal meningiomas: A 20 year review
AT King, MM Sharr, RW Gullan, JR Bartlett
British Journal of Neurosurgery.
1998;12(6):521-526
85. Free alpha subunit and intact TSH secretion in vitro are closely associated in human somatotroph adenoma
SJB Aylwin, AT King, A Blenke, J Geddes, DF Wood, JP Monson, JM Burrin.
European Journal of Endocrinology. 139(4):378-86, 1998.
86. Carbon fibre cage implantation for treatment of cervical spine disorders.
NSR Brooke, AT King, AM Hussein, RW Gullan
British Journal of Neurosugery 1997;11(3):221-227.
OTHER PUBLICATIONS:
1. Intraoperative supratentorial extradural haematoma complicating excision of a giant vestibular schwannoma.
Lewis DG, Lloyd S, Pathmanaban ON, Ward C, Rutherford SA, King AT.
World Neurosurg. 2016 Jan 21.
2. Giant Cell Reparative Granuloma of the Temporal Bone:case study with a radiological focus
Dowling M, Camillieri A, King A, Herwadkar A, du Plessis D, Lloyd S.
The otolaryngologist, 2015;8(2):103-105
3. Traumatic extradural haematoma revealed after contralateral decompressive craniectomy.
Nadig AS, King AT
Br J Neurosurg. 2012 Jul 4 [Epub ahead of print]
4. A case of acute compressive optic neuropathy secondary to aneurysmal bone cyst formation in fibrous dysplasia.
MacNally SP, Ashida R, Williams TJ, King AT, Leatherbarrow B, Rutherford SA.
Br J Neurosurg. 2010 Dec;24(6):705-7
5. Endoscopic transsphenoidal surgery for isolated dysplasia of the clivus.
Singh N, Abou-Zeid A, King A, du Plessis D, Gnanalingham K
Minim Invasive Neurosurg. 2009 Aug;52(4):190-2.
6. Brain hyperthermia after traumatic brain injury does not reduce brain oxygen.
Childs C, Sacho RH, King AT
Neurosurgery, 2009 Jun: 64(6):E1206 (letter)
7. Acute external hydrocephalus complicating craniocervical decompression for syringomyelia-Chiari 1 complex.
Perrini P, Rawlinson A, Cowie RA, King AT.
Neurosurg Rev. 2008 Jul;31(3):331-5.
8. Neurointensivists
Patel HC, King AT, Lecky F
J Neurosurg. 2007 Jan;106(1):194-5 (letter)
9. Rupture of brain stem cyst with clinical benefit after head injury.
Hussain Z Balamurali G King AT.
J Neurosurgery (1 suppl Pediatrics) 106:41-43, 2007.
10. Early recurrence of an intracranial epidermoid cyst due to low grade infection.
Rutherford SA, Leach PA, King AT
Skull Base 2006 May; 16(2): 109-16
11. Cerebral Abscess as a delayed complication of halo fixation.
Ray A, Iyer RV, King AT
Acta Neurochir (Wein) 2006 148: 1015-1016
12. Management of the patient and family with neurofibromatosis 2: a consensus conference statement.
Evans DGR, Baser ME, O’Reilly B, Rowe J, Gleeson M, Saeed S, King A, Huson SM, Kerr R, Thomas N, Irving R, Macfarlane R, Ferner R, McLeod R, Moffat D, Ramsden R.
British Journal of Neurosurgery Feb 2005: 19(1): 5-12
13. Temperature measurement after severe head injury.
Child C, Hadcock J, Ray A, King AT, Protheroe R.
Anaesthesia 2004 59 (2) 192-193 (letter)
14. Pregnancy related pituitary enlargement mimicking macroadenoma.
Heald AH, Hughes D, King A, Buckler H.
British Journal of Neurosurgery. Oct 2004 18(5):524-6.
15. Unusual penetrating mechanism for an intracranial foreign body.
Ray A, Sen A, King AT, Thorne JT.
British Medical Journal 2000:320;1018
16. Cysto-peritoneal shunt infection with Trichosporon Beigelii.
RD Ashpole, K Jacobson, AT King, AE Holmes
British Journal of Neurosurgery 1991; 5(5): 515-7
